A key part of our work until 2023 will be improving the management of cholesterol. Good management of cholesterol is important in preventing heart attacks and strokes, but patients with high cholesterol are likely to be asymptomatic.


Tackling Cholesterol Together - education programme


The Innovation Agency is part of a collaboration led by the NHS Accelerated Access Collaborative (AAC), the AHSN Network and cholesterol charity, HEART UK, to deliver an education programme for healthcare professionals around cholesterol.

Tackling Cholesterol Together supports the NHS England and NHS Improvement (NHSEI) three-year lipids workstream, to raise awareness that Cardiovascular Disease (CVD) is preventable yet currently kills 136,00 people every year.

The programme will support healthcare professionals to address under diagnosis and under treatment at scale; and use new models to manage cholesterol, underpinned by an updated NICE-endorsed pathway, with certificates issued for completion of all content.

Tackling Cholesterol Together will be delivered though videos, podcasts, webinars, expert clinics and online modules. Topics covered range from statin intolerance to behavioural change, Familial Hypercholesterolaemia (FH), novel therapies on the horizon, and much more.

For more information please go to


Familial hypercholesterolemia



We are supporting national ambitions to improve cholesterol management and the identification and management of familial hypercholesterolemia (FH), a hereditary condition of high cholesterol that is evident from birth but is rarely picked up before the individual has a CVD event.

Listen to a podcast featuring a 34 year old mum who had a heart attack while pregnant due to familial hypercholesterolemia; plus a national clinical leader on the AHSN Network lipids programme


Parent-child screening for familial hypercholesterolemia

The Innovation Agency is one of seven AHSNs taking part in a national parent-child screening programme to detect familial hypercholesterolemia. Infants will be offered a heel prick at their appointment to be tested at the surgery for elevated cholesterol. If high cholesterol levels are detected the sample will be sent to the regional genomics hub for genetic testing. If familial hypercholesterolemia is identified the family can receive genetic counselling and be registered as having the condition and offered treatment.

For more details on the programme, please contact Innovation Agency Project Manager


System levers to achieve CVD ambitions

Public Health England has identified lipids management as a key area of improvement. Over the next three years, the AHSN programme will focus on:


detection of people with FH


improvement in the management of people with resistant high cholesterol


Key national support initiatives

CVDPrevent audit     find out more
A national audit that will identify key areas of improvement for primary care, to report in April 2021

Directed Enhanced Service (DES) scheme      find out more
A national programme to support primary care in achieving improvements 2021/2022

Accelerated Access Collaborative    find out more
A number of products have been funded through this approach, including PCSK9i

NICE-endorsed pathways for lipids and statins intolerance
Supporting clinical guidance CG181, CG 71, and technology assessments TA385, TA394



Outcomes will be measured in accordance with national metrics:

Improving the numbers of patients with high cholesterol managed in accordance with NICE guidance

Increasing the numbers of patients identified with FH

Improving the number of appropriate referrals to lipid clinics

Increasing the numbers of patients with a recorded cholesterol reading that is optimised.


Current projects

We currently have several improvement projects with primary and secondary care:

  1. Liverpool lipids improvement project
  2. Halton primary care lipids improvement project (Control Cholesterol)
  3. Knowsley community pharmacy lipids improvement project (Control Cholesterol)

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